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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLCO1B3
All Species:
8.79
Human Site:
S243
Identified Species:
27.62
UniProt:
Q9NPD5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPD5
NP_062818.1
702
77403
S243
D
I
G
Y
V
D
L
S
T
I
R
I
T
P
K
Chimpanzee
Pan troglodytes
XP_520785
691
76351
S243
D
I
G
Y
V
D
L
S
T
V
R
I
T
P
T
Rhesus Macaque
Macaca mulatta
NP_001028113
702
77320
S243
D
I
G
Y
V
D
L
S
T
I
R
I
T
P
K
Dog
Lupus familis
XP_852867
712
78816
D259
D
I
G
F
V
N
L
D
H
V
T
I
T
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJL3
689
76710
R238
D
V
G
Y
V
D
L
R
S
V
R
I
T
P
Q
Rat
Rattus norvegicus
Q9QZX8
652
72748
I215
T
L
H
T
I
A
M
I
G
P
I
L
G
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416418
711
78133
G261
D
V
G
F
V
D
L
G
K
I
A
I
T
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038462
689
75417
V249
S
V
C
A
K
I
Y
V
D
I
G
F
V
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.9
92.8
45
N.A.
65
60.4
N.A.
N.A.
48.9
N.A.
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87.3
96.4
64.4
N.A.
79.3
74.2
N.A.
N.A.
67.5
N.A.
65.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
100
60
N.A.
66.6
0
N.A.
N.A.
60
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
80
N.A.
93.3
26.6
N.A.
N.A.
80
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
13
0
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
0
0
63
0
13
13
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
25
0
0
0
0
0
0
0
13
0
13
0
% F
% Gly:
0
0
75
0
0
0
0
13
13
0
13
0
13
0
0
% G
% His:
0
0
13
0
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
13
13
0
13
0
50
13
75
0
0
13
% I
% Lys:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
38
% K
% Leu:
0
13
0
0
0
0
75
0
0
0
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
13
0
0
0
75
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% Q
% Arg:
0
0
0
0
0
0
0
13
0
0
50
0
0
0
0
% R
% Ser:
13
0
0
0
0
0
0
38
13
0
0
0
0
0
0
% S
% Thr:
13
0
0
13
0
0
0
0
38
0
13
0
75
0
13
% T
% Val:
0
38
0
0
75
0
0
13
0
38
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _